Introducing QPatch HTX - the newest automated patch clamp system from Sophion. It builds on the QPatch technology already appreciated in the global pharmaceutical industry. The QPatch HTX is a 48-channel patch clamp system that works in both a multi-hole mode, ideal for screening, and single-hole mode, ideal for compound profiling. It can be applied to both voltage- and ligand-gated ion channels.
Upgrades of existing QPatch HT systems to QPatch HTX are available now.
- Increased throughput with up to 7000 data points per day
- Screening and compound profiling assays on the same instrument
- Runs in both multi-hole and single-hole mode
- For all ligand- and voltage-gated ion channels
- 8 pipette liquid handling robot with intelligent experiment planning
- High-quality recordings with true gigaseals
- Micro-fluidic channels for rapid solution exchange
- User-friendly touchscreen for easy experiment execution
- Unattended operation for several hours
- Automated data analysis, with highly sophisticated analysis tool

Multi-hole experiments improve success rates significantly as compared to single-hole experiments, because it measures the total current from multiple cells at a time. This means that low- and non-expressors often found in e.g. transient expression systems are no longer a problem. It also means that small endogenous ion channel currents can now be examined easily.
For more information on QPatch HTX please contact us.
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