Sophion

QPatch 16X - multi-hole patch clamp

The multi-hole version of QPatch 16, the QPatch 16X is now available. The QPatch 16X has all the well-known benefits of QPatch 16, and in addition the QPatch 16X can run multi-hole patch clamp experiments. The QPatch 16X also works in single-hole mode like a traditional QPatch 16 - the actual mode of operation depends on whether the system is loaded with traditional single-hole QPlates or the new multi-hole QPlates.

  • Screening and compound profiling assays on the same instrument
  • Runs in both multi-hole and single-hole mode
  • For all ligand- and voltage-gated ion channels
  • 4 pipette liquid handling robot with intelligent experiment planning
  • High-quality recordings with true gigaseals
  • Micro-fluidic channels for rapid solution exchange
  • User-friendly touchscreen for easy experiment execution
  • Unattended operation for several hours
  • Automated data analysis with highly sophisticated analysis tool

The multi-hole technology is especially suited for ion channels with low conductance and/or cell lines with a large heterogeneity of ion channel expression levels, such as cell lines with transiently transfected ion channels. The multi-hole technology provides nearly 100% success rate and therefore the highest possible throughput and the lowest possible price per data point.

Existing QPatch HT and QPatch 16 systems are on-site upgradeable to the new multi-hole technology.

For more information on QPatch 16X please contact us.

 


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